From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

Revolutionize Your Mycobacterium Tuberculosis Research with MGI's Cutting-Edge ATOPLEX & MTB-Explorer Software

Next Generation Sequencing has provided insights into the genetic diversity of Mycobacterium Tuberculosis, which are crucial for understanding the evolution and transmission of the disease, including the identification of drug-resistant strains, enabling rapid and accurate tailoring of treatment.

MGI has developed an ATOPlex Mycobacterium Tuberculosis targeted sequencing sample to report workflow, providing full and complete MTB identification and drug resistance analysis. Based on MGI’s ATOPlex multiplex PCR library preparation platform, 2-step amplification in one tube is needed to achieve target area amplification and library construction, supporting direct detection of nucleic acid extracted from sputum and lavage fluid samples.

Combined with MGI’s MTB-Explorer Software, provides identification of 174 types of mycobacteria, MTBC identification, spoligotyping, and evolutionary traceability analysis. Specifically for drug resistance, the software covers a total of 7000+ mutations, including all of the 1200+ first-and second-group drug resistance associated mutations associated with the “Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance" released by WHO for annotation.

MGI's ATOPlex Mycobacterium Tuberculosis targeted sequencing workflow Sample to report in as fast as 24h

DNA Extraktion & Bibliotheksvorbereitung

~7-8h
  • ATOPlex MTB Library Preperation Set

  • DNBSEQ OneStep Make DNB Reagent Kit V4.0 (Dua Barcode)

ATOplex Library preperation reagents

DNA Extraktion & Bibliotheksvorbereitung

~12-20h
  • High-throughput Sequencing Set

  • DNBSEQ-G99 SM FCL PE150 12h

  • DNBSEQ-E25 FCL PE150 20h

Ein Bild des DNBSEQ-G99 Sequenziergeräts von MGI-Tech

DNA Extraktion & Bibliotheksvorbereitung

~2-6h
  • MTB-Explorer Software

MTB-Explorer Software

Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)

DNA Extraktion & Bibliotheksvorbereitung

DNA Extraktion & Bibliotheksvorbereitung

Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Daten
Qualitätskontrolle
Saubere Daten
MTBC-Arten
Referenz
Artenidentifikation
Negatives/Positives
Urteil
Negativer
Bericht
Positiv
M. Tuberkulose
Referenz
(H37Rv)
Ausrichtung
Abstammung &
Spoligotyp
Abstammung &
Spoligotyp-
ergebnisse
Variantenaufruf
Konsensus
Sequenz
Evolutionäre Analyse (Baum)
Evolutionäre Analyse (Baum)
Anmerkung
MTB Arzneimittelresistenz-Datenbank
Arzneimittelresistenz
Vorhersageergebnisse

Next-Generation-Metagenomik mit DNBSEQ-G99

Beispiel für genetischen Code: Sequenzierung mit Lichtgeschwindigkeit!

Bibliotheksvorbereitung

Sequenzierung

Datenanalyse

Stuhl-DNA (Meta) Extraktionskit, Verbesserte Metagenomik:
Optimierte Stuhldna-Extraktion mit MGISP-NE384/MGISP-960 für umfassende metagenomische Analysen.

Stuhl-DNA (Meta) Extraktionskit, Verbesserte Metagenomik:
Optimierte Stuhldna-Extraktion mit MGISP-NE384/MGISP-960 für umfassende metagenomische Analysen.

Stuhl-DNA (Meta) Extraktionskit, Verbesserte Metagenomik:
Optimierte Stuhldna-Extraktion mit MGISP-NE384/MGISP-960 für umfassende metagenomische Analysen.

Stuhl-DNA (Meta) Extraktionskit, Verbesserte Metagenomik:
Optimierte Stuhldna-Extraktion mit MGISP-NE384/MGISP-960 für umfassende metagenomische Analysen.

MGISP-100 Automationsmaschine von MGI-Tech

Kombinieren Sie Präzision und Leistung mit dem DNBSEQ-G99

DNBSEQ-G99

DNBSEQ-E25

Beispiel pro Lauf Icon
Proben pro Lauf

≤8 samples /FC

MGI-Flowzellen-Symbol
Flusszellen

1

Längen lesen

FCL PE150

Zeit

30h

DNBSEQ-G99

DNBSEQ-E25

Beispiel pro Lauf Icon
Proben pro Lauf

≤24 samples /FC

MGI-Flowzellen-Symbol
Flusszellen

2

Längen lesen

FCL PE150

Zeit

24h

Zertifizierung

ISO 13485

Qualitätsmanagementsystem für Medizinprodukte

ISO 14001

Umweltmanagementsystem

ISO 27001

Informations-Sicherheitsmanagementsystem

Zertifizierung

ISO 13485

Qualitätsmanagementsystem für Medizinprodukte

ISO 14001

Umweltmanagementsystem

ISO 27001

Informations-Sicherheitsmanagementsystem

Zertifizierung

ISO 13485

Qualitätsmanagementsystem für Medizinprodukte

ISO 14001

Umweltmanagementsystem

ISO 27001

Informations-Sicherheitsmanagementsystem

Zertifizierung

ISO 13485

Qualitätsmanagementsystem für Medizinprodukte

ISO 14001

Umweltmanagementsystem

ISO 27001

Informations-Sicherheitsmanagementsystem

Ressourcen

Brochure & Manuals

Ressourcen

Brochure & Manuals

Urheberrecht © 2024 MGI tech GmbH, Ltd. Alle Rechte vorbehalten.

Urheberrecht © 2024 MGI tech GmbH, Ltd. Alle Rechte vorbehalten.

Urheberrecht © 2024 MGI tech GmbH, Ltd. Alle Rechte vorbehalten.