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From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

Revolutionize Your Mycobacterium Tuberculosis Research with MGI's Cutting-Edge ATOPLEX & MTB-Explorer Software

Next Generation Sequencing has provided insights into the genetic diversity of Mycobacterium Tuberculosis, which are crucial for understanding the evolution and transmission of the disease, including the identification of drug-resistant strains, enabling rapid and accurate tailoring of treatment.

MGI has developed an ATOPlex Mycobacterium Tuberculosis targeted sequencing sample to report workflow, providing full and complete MTB identification and drug resistance analysis. Based on MGI’s ATOPlex multiplex PCR library preparation platform, 2-step amplification in one tube is needed to achieve target area amplification and library construction, supporting direct detection of nucleic acid extracted from sputum and lavage fluid samples.

Combined with MGI’s MTB-Explorer Software, provides identification of 174 types of mycobacteria, MTBC identification, spoligotyping, and evolutionary traceability analysis. Specifically for drug resistance, the software covers a total of 7000+ mutations, including all of the 1200+ first-and second-group drug resistance associated mutations associated with the “Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance" released by WHO for annotation.

MGI's ATOPlex Mycobacterium Tuberculosis targeted sequencing workflow Sample to report in as fast as 24h

Extraction d'ADN et préparation de la bibliothèque

~7-8h
  • ATOPlex MTB Library Preperation Set

  • DNBSEQ OneStep Make DNB Reagent Kit V4.0 (Dua Barcode)

ATOplex Library preperation reagents

Extraction d'ADN et préparation de la bibliothèque

~12-20h
  • High-throughput Sequencing Set

  • DNBSEQ-G99 SM FCL PE150 12h

  • DNBSEQ-E25 FCL PE150 20h

Une photo du séquenceur DNBSEQ-G99 de MGI-Tech

Extraction d'ADN et préparation de la bibliothèque

~2-6h
  • MTB-Explorer Software

MTB-Explorer Software

Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)

Extraction d'ADN et préparation de la bibliothèque

Extraction d'ADN et préparation de la bibliothèque

Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Data
Quality control
Clean data
MTBC species
reference
Species identification
Negative/Positive
judgement
Negative
report
Positive
M.tuberculosis
reference
(H37Rv)
Alignment
Lineage &
Spoligotype
Lineage &
Spoligotype
results
Variant Calling
Consensus
sequence
Evolutionary analysis (Tree)
Evolutionary analysis (Tree)
Annotation
MTB drug resistance database
Drug Resistance
Prediction results

Métagénomique de prochaine génération avec DNBSEQ-G99

De l'échantillon au code génétique : séquençage à la vitesse de la lumière !

Préparation de la bibliothèque

Séquençage

Analyse des données

Kit d'extraction d'ADN fécal (Méta), métagénomique améliorée:
Extraction simplifiée de l'ADN fécal avec MGISP-NE384/MGISP-960 pour une analyse métagénomique complète.

Kit d'extraction d'ADN fécal (Méta), métagénomique améliorée:
Extraction simplifiée de l'ADN fécal avec MGISP-NE384/MGISP-960 pour une analyse métagénomique complète.

Kit d'extraction d'ADN fécal (Méta), métagénomique améliorée:
Extraction simplifiée de l'ADN fécal avec MGISP-NE384/MGISP-960 pour une analyse métagénomique complète.

Kit d'extraction d'ADN fécal (Méta), métagénomique améliorée:
Extraction simplifiée de l'ADN fécal avec MGISP-NE384/MGISP-960 pour une analyse métagénomique complète.

Machine d'automatisation MGISP-100 de MGI-Tech

Combinez précision et performance avec le DNBSEQ-G99

DNBSEQ-G99

DNBSEQ-E25

Icône d'échantillons par exécution
Échantillons par exécution

≤8 samples /FC

Icône des cellules MGI Flow
Cellules de flux

1

Longueurs de lecture

FCL PE150

Temps

30h

DNBSEQ-G99

DNBSEQ-E25

Icône d'échantillons par exécution
Échantillons par exécution

≤24 samples /FC

Icône des cellules MGI Flow
Cellules de flux

2

Longueurs de lecture

FCL PE150

Temps

24h

Certification

ISO 13485

Système de gestion de la qualité des dispositifs médicaux

ISO 14001

Système de gestion environnementale

ISO 27001

Système de gestion de la sécurité de l'information

Certification

ISO 13485

Système de gestion de la qualité des dispositifs médicaux

ISO 14001

Système de gestion environnementale

ISO 27001

Système de gestion de la sécurité de l'information

Certification

ISO 13485

Système de gestion de la qualité des dispositifs médicaux

ISO 14001

Système de gestion environnementale

ISO 27001

Système de gestion de la sécurité de l'information

Certification

ISO 13485

Système de gestion de la qualité des dispositifs médicaux

ISO 14001

Système de gestion environnementale

ISO 27001

Système de gestion de la sécurité de l'information

Ressources

Brochure & Manuals

Ressources

Brochure & Manuals