Breakthroughs in Agrigenomics: MGI Revolutionizes Molecular Breeding

Advances in Molecular Breeding

Molecular breeding plays a crucial role in improving crop and livestock production. MGI is committed to facilitating breakthroughs in molecular breeding applications by continuously expanding the capabilities of its sequencing platforms. One such innovation is the ATOPlex platform, based on MGI's self-developed multiplex PCR technology. The ATOPlex platform offers targeted genome sequencing with specific multiplex PCR primers, saving time and cost while providing more information from even small samples. It demonstrates scalable genotyping technology and reproducible results.

In a research project focusing on grouper, the ATOPlex platform showcased exceptional performance with high prediction accuracy for grouper body weight and ammonia tolerance. Additionally, it achieved a high detection rate for different grouper species. MGI's sequencers have also enabled simplified genome sequencing for population analysis and low coverage whole-genome sequencing (lcWGS) of large cohorts, streamlining the breeding process for livestock and poultry

Contributions of DNBSEQ™ Sequencing Platforms

MGI's DNBSEQ™ sequencing platforms are designed to accelerate the molecular breeding process, from sample pre-processing to library preparation, sequencing, and bioinformation analysis. The company offers automated sample processing systems that significantly speed up pre-processing efficiency, such as the MGISTP-7000 High-Throughput Automated Sample Transfer Processing System and the MGISP-960 High-Throughput Automated Sample Preparation System. These systems eliminate manual operations, improve stability, reduce costs, and enhance overall work efficiency in molecular breeding applications.

MGI's proprietary DNBSEQ™ sequencing technology delivers high accuracy, decreased duplicates, and extremely low index hopping rates compared to other sequencing technologies. With different sequencer models available, ranging from DNBSEQ-G50 to DNBSEQ-G400 and DNBSEQ-T7, MGI caters to diverse sample sizes and detection speeds required by companies, research institutes, and government agencies involved in molecular breeding applications.

To complete the workflow, MGI offers the Molecular Breeding Analysis System, an all-in-one computing workstation for data storage and processing. This system, combined with MGI's technology, enables efficient and cost-effective molecular breeding applications.

MGI's sequencing technology and platforms have revolutionized agrigenomics research and molecular breeding, contributing to advancements in basic scientific research and the development of improved breeding strategies. Through innovations like stLFR and the ATOPlex platform, MGI has addressed the limitations of traditional sequencing methods, enabling more accurate and cost-effective de novo sequencing and targeted genome sequencing. The company's automated sample processing systems and DNBSEQ™ sequencing platforms have streamlined the molecular breeding workflow, enhancing efficiency and reducing costs.

To learn more about how MGI's sequencing technology empowers agrigenomics development, visit here. For detailed information about MGI's Agriculture Genome Grant, you can now view our on demand webinar here.