From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

From sample-to-report: Rapid MTB identification, drug resistance, and traceability solution

Full rapid process and reporting

Targeted and streamlined operation with MGI ATOPLEX technology

Full rapid process and reporting

Full rapid process and reporting

Suitable for culture-free sample

Suitable for culture-free sample

Comprehensive software analysis

Comprehensive software analysis

Revolutionize Your Mycobacterium Tuberculosis Research with MGI's Cutting-Edge ATOPLEX & MTB-Explorer Software

Next Generation Sequencing has provided insights into the genetic diversity of Mycobacterium Tuberculosis, which are crucial for understanding the evolution and transmission of the disease, including the identification of drug-resistant strains, enabling rapid and accurate tailoring of treatment.

MGI has developed an ATOPlex Mycobacterium Tuberculosis targeted sequencing sample to report workflow, providing full and complete MTB identification and drug resistance analysis. Based on MGI’s ATOPlex multiplex PCR library preparation platform, 2-step amplification in one tube is needed to achieve target area amplification and library construction, supporting direct detection of nucleic acid extracted from sputum and lavage fluid samples.

Combined with MGI’s MTB-Explorer Software, provides identification of 174 types of mycobacteria, MTBC identification, spoligotyping, and evolutionary traceability analysis. Specifically for drug resistance, the software covers a total of 7000+ mutations, including all of the 1200+ first-and second-group drug resistance associated mutations associated with the “Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance" released by WHO for annotation.

MGI's ATOPlex Mycobacterium Tuberculosis targeted sequencing workflow Sample to report in as fast as 24h

Извлечение ДНК и подготовка библиотеки

~7-8h
  • ATOPlex MTB Library Preperation Set

  • DNBSEQ OneStep Make DNB Reagent Kit V4.0 (Dua Barcode)

ATOplex Library preperation reagents

Извлечение ДНК и подготовка библиотеки

~12-20h
  • High-throughput Sequencing Set

  • DNBSEQ-G99 SM FCL PE150 12h

  • DNBSEQ-E25 FCL PE150 20h

Фотография секвенатора DNBSEQ-G99 от MGI-Tech

Извлечение ДНК и подготовка библиотеки

~2-6h
  • MTB-Explorer Software

MTB-Explorer Software

Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)

Извлечение ДНК и подготовка библиотеки

Извлечение ДНК и подготовка библиотеки

Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Precisely analyze and annotate drug resistance and explore with MTB-Explorer Software (ATOPLex)
Data
Quality control
Clean data
MTBC species
reference
Species identification
Negative/Positive
judgement
Negative
report
Positive
M.tuberculosis
reference
(H37Rv)
Alignment
Lineage &
Spoligotype
Lineage &
Spoligotype
results
Variant Calling
Consensus
sequence
Evolutionary analysis (Tree)
Evolutionary analysis (Tree)
Annotation
MTB drug resistance database
Drug Resistance
Prediction results

Метагеномика нового поколения с DNBSEQ-G99

Пример генетического кода: секвенирование на сверхвысокой скорости!

Подготовка библиотеки

Последовательность

Анализ данных

Набор для извлечения ДНК из стула (Meta), улучшенная метагеномика:
Упрощенное извлечение ДНК из стула с использованием MGISP-NE384/MGISP-960 для комплексного метагеномного анализа.

Набор для извлечения ДНК из стула (Meta), улучшенная метагеномика:
Упрощенное извлечение ДНК из стула с использованием MGISP-NE384/MGISP-960 для комплексного метагеномного анализа.

Набор для извлечения ДНК из стула (Meta), улучшенная метагеномика:
Упрощенное извлечение ДНК из стула с использованием MGISP-NE384/MGISP-960 для комплексного метагеномного анализа.

Набор для извлечения ДНК из стула (Meta), улучшенная метагеномика:
Упрощенное извлечение ДНК из стула с использованием MGISP-NE384/MGISP-960 для комплексного метагеномного анализа.

Автоматизированная машина MGISP-100 от MGI-Tech

Объедините точность и производительность с DNBSEQ-G99

DNBSEQ-G99

DNBSEQ-E25

Иконка образцов на один запуск
Образцы на запуск

≤8 samples /FC

Иконка потоковых ячеек MGI
Потоковые ячейки

1

Длины чтения

FCL PE150

Время

30h

DNBSEQ-G99

DNBSEQ-E25

Иконка образцов на один запуск
Образцы на запуск

≤24 samples /FC

Иконка потоковых ячеек MGI
Потоковые ячейки

2

Длины чтения

FCL PE150

Время

24h

Сертификация

ISO 13485

Система управления качеством медицинских изделий

ISO 14001

Система управления окружающей средой

ISO 27001

Система управления информационной безопасностью

Сертификация

ISO 13485

Система управления качеством медицинских изделий

ISO 14001

Система управления окружающей средой

ISO 27001

Система управления информационной безопасностью

Сертификация

ISO 13485

Система управления качеством медицинских изделий

ISO 14001

Система управления окружающей средой

ISO 27001

Система управления информационной безопасностью

Сертификация

ISO 13485

Система управления качеством медицинских изделий

ISO 14001

Система управления окружающей средой

ISO 27001

Система управления информационной безопасностью

Ресурсы

Brochure & Manuals

Ресурсы

Brochure & Manuals